Los Altos, CA, United States of America

John J Perumattam


Average Co-Inventor Count = 5.7

ph-index = 7

Forward Citations = 439(Granted Patents)


Company Filing History:


Years Active: 2001-2009

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19 patents (USPTO):Explore Patents

Title: **John J Perumattam: Innovator in Medicinal Chemistry**

Introduction

John J Perumattam is a notable inventor based in Los Altos, California, recognized for his significant contributions to the field of medicinal chemistry. With a remarkable portfolio of 19 patents, his work primarily focuses on developing novel compounds for therapeutic applications, particularly in the area of kinase inhibitors.

Latest Patents

Among his latest innovations is a patent titled "Indole-type derivatives as inhibitors of p38 kinase." This invention pertains to methods for inhibiting p38-α kinase using specific compounds that feature a phenyl or thienyl group linked through a piperidine or piperazine nucleus to an indole residue. Notably, the indole residue must have a substituent on the ring nitrogen that is either an amino or substituted amino group. Another significant patent is for "Pyrido-pyrimidine compounds as medicaments," which involves methods to inhibit TGF-β and/or p38-α kinase using defined chemical structures and their pharmaceutically acceptable salts.

Career Highlights

John J Perumattam's career is marked by his dedication to research and innovation in therapeutic development. His work has contributed significantly to understanding and treating diseases by targeting specific biological pathways. His expertise in medicinal chemistry is evident in the innovative compounds he has developed that are aimed at enhancing drug efficacy.

Collaborations

Throughout his career, John has collaborated with esteemed colleagues such as Sundeep Dugar and Sarvajit Chakravarty at Scios Inc. Their collaborative efforts have culminated in groundbreaking research that holds promise for future medical advancements.

Conclusion

John J Perumattam represents the epitome of innovation within the pharmaceutical industry. His extensive patent portfolio reflects a commitment to enhancing therapeutic options through scientific exploration and collaboration. With a focus on kinase inhibitors, his contributions will undoubtedly leave a lasting impact on drug development and patient care.

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