John J Hufnagel

Title: The Innovations of John J Hufnagel

Introduction

John J Hufnagel is a notable inventor based in Waukegan, IL (US). He has made significant contributions to the field of pharmaceuticals, holding a total of 7 patents. His work primarily focuses on the development of non-ionic contrast agents and novel methods for synthesizing important pharmaceutical compounds.

Latest Patents

One of Hufnagel's latest patents is a process for the preparation of iopamidol. This invention discloses a method for creating pure non-ionic contrast agents, along with a purification technique for these agents. Another significant patent involves the preparation of fluticasone and related 17β-carbothioic esters. This invention introduces a novel method for converting carboxylic acids to carbothioic acids, which is applied in the preparation of androstane carbothiolates, such as fluticasone propionate, while avoiding the need for column chromatography.

Career Highlights

Throughout his career, Hufnagel has worked with prominent companies in the pharmaceutical industry, including Bracco Imaging S.p.A. and Abbott Laboratories Corporation. His expertise and innovative approaches have made a lasting impact on the development of pharmaceutical products.

Collaborations

Hufnagel has collaborated with notable professionals in his field, including Ashok V Bhatia and Steven A Chamberlin. These collaborations have contributed to the advancement of his research and the successful development of his inventions.

Conclusion

John J Hufnagel's contributions to the field of pharmaceuticals through his innovative patents and collaborations highlight his importance as an inventor. His work continues to influence the development of essential medical products.