Company Filing History:
Years Active: 1995
Title: John Harrison: Innovator in Lithium Aminoborohydrides
Introduction
John Harrison is a notable inventor based in Santa Cruz, CA (US). He has made significant contributions to the field of chemistry, particularly in the development of powerful reducing agents known as lithium aminoborohydrides. His innovative work has implications for various chemical reactions and applications.
Latest Patents
Harrison holds a patent for the "Synthesis of lithium aminoborohydrides and reactions thereof." This invention relates to novel reducing agents that are prepared by the addition of BH3·THF to the corresponding dialkylamine at 25°C. The resulting amineborane complex undergoes deprotonation by a strong base, such as n-BuLi, yielding the aminoborohydride quantitatively. These lithium aminoborohydrides are powerful reducing agents, comparable in strength to lithium aluminum hydride. The unique activity and selectivity of lithium pyrrolidinoborohydride in reducing various functional groups make it a valuable tool in organic synthesis.
Career Highlights
John Harrison is affiliated with the University of California, where he conducts research and develops innovative chemical solutions. His work has garnered attention for its potential applications in reducing esters, lactones, and anhydrides to corresponding alcohols, while demonstrating selectivity in not reducing carboxylic acids.
Collaborations
Harrison has collaborated with esteemed colleagues such as Bakthan Singaram and Gary B. Fisher. Their combined expertise has contributed to advancements in the field of chemistry and the development of new reducing agents.
Conclusion
John Harrison's contributions to the synthesis of lithium aminoborohydrides highlight his innovative spirit and dedication to advancing chemical research. His work continues to influence the field and offers promising applications in various chemical processes.