John H Pruett

Title: John H Pruett: Innovator in Veterinary Vaccines and Monoclonal Antibodies

Introduction

John H Pruett is a notable inventor based in Kerrville, TX (US). He has made significant contributions to the field of veterinary medicine, particularly in the development of vaccines and monoclonal antibodies. With a total of 2 patents, his work has had a profound impact on animal health.

Latest Patents

Pruett's latest patents include innovative solutions for protecting cattle from psoroptic scabies. One patent discloses a novel antigenic protein that effectively stimulates antibody production in animals against the sheep scab mite. This protein not only provides protection from infestation but also elicits an immediate-type hypersensitivity response in cattle. Additionally, he has developed monoclonal antibodies to the crystal protein of Bacillus thuringiensis. This work involved constructing murine hybridomas by fusing spleen cells from BALB/c mice with a murine myeloma cell line. His modified ELISA method for detecting specific antibodies has significantly increased sensitivity, allowing for the identification of hybridomas that secrete monoclonal antibodies specific for the B.t.i. crystal protein.

Career Highlights

Throughout his career, Pruett has worked with esteemed organizations, including the United States of America as represented by the Secretary of Agriculture. His contributions have been pivotal in advancing veterinary immunology and enhancing the effectiveness of vaccines.

Collaborations

Pruett has collaborated with notable colleagues such as Kevin B Temeyer and Maurice Haufler. Their combined expertise has furthered research and development in the field of veterinary medicine.

Conclusion

John H Pruett's innovative work in developing vaccines and monoclonal antibodies has made a significant impact on animal health. His contributions continue to influence the field and improve the welfare of livestock.