John Griffith Jones

Title: John Griffith Jones: Innovator in Metabolic Research

Introduction

John Griffith Jones is a notable inventor based in Coimbra, Portugal. He has made significant contributions to the field of metabolic research, holding 2 patents that focus on innovative methods for understanding metabolic processes.

Latest Patents

One of his latest patents is titled "Methods of distinguishing between glutamine formed by cataplerosis or proteolysis." This invention relates to methods for distinguishing between glutamine produced through different metabolic pathways. The process involves assaying a sample from a subject for deuteriated glutamine after administering deuteriated water and an agent that promotes glutamine excretion. This method is particularly useful in clinical settings, such as testing for proteolysis in patients or detecting anabolic drug abuse in athletes.

Another significant patent by Jones is "Measurement of gluconeogenesis and intermediary metabolism using stable isotopes." This invention provides a combination of carbon-13 and deuterium metabolic tracers, which, when used with nuclear magnetic resonance spectroscopy, allow for the measurement of metabolic fluxes in target organisms. The tracers can be taken orally during clinical exams, and the resulting metabolic information can be derived from blood, urine, or other fluids, offering a comprehensive profile of glucogenic metabolism. This subject matter is applicable to studying metabolic dysfunctions related to obesity, diabetes, HIV infection, and various other disease conditions.

Career Highlights

Throughout his career, John Griffith Jones has worked with esteemed institutions, including the University of Texas System and Biocant - Associação de Transferência de Tecnologia. His work has significantly advanced the understanding of metabolic processes and their implications for health.

Collaborations

Jones has collaborated with notable professionals in his field, including Craig R Malloy and A Dean Sherry. These collaborations have further enriched his research and contributed to the development of his innovative patents.

Conclusion

John Griffith Jones is a distinguished inventor whose work in metabolic research has led to valuable patents that enhance our understanding of metabolic processes. His contributions are vital for clinical applications and the study of various health conditions.