John G Menke

Title: The Innovations of John G Menke

Introduction

John G Menke is a notable inventor based in Morganville, NJ (US). He has made significant contributions to the field of biochemistry, particularly in the area of receptor biology. With a total of 4 patents to his name, Menke's work has advanced our understanding of bradykinin receptors.

Latest Patents

Menke's latest patents include groundbreaking research on bradykinin B1 receptor antibodies. His work involves cloning and characterizing DNAs encoding bradykinin B receptors from mammalian cells. The recombinant receptor he developed is capable of forming receptors that bind des-Arg kallidin and other B-specific ligands. Furthermore, the DNA has been expressed in recombinant host cells, which produce active recombinant protein. This innovative approach has also led to the establishment of methods for identifying modulators of receptor activity. Another significant patent focuses on purified bradykinin B1 receptors, where similar cloning and characterization techniques have been applied.

Career Highlights

Menke is currently employed at Merck & Company, Inc., a leading global healthcare company. His role at Merck has allowed him to collaborate with other experts in the field and contribute to important research initiatives.

Collaborations

Some of his notable coworkers include David L Linemeyer and John W Hess. Their collaborative efforts have further enhanced the research and development of receptor biology.

Conclusion

John G Menke's contributions to the field of biochemistry, particularly through his patents on bradykinin receptors, highlight his innovative spirit and dedication to scientific advancement. His work continues to influence the understanding of receptor biology and its applications in medicine.