This inventor holds 2 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Georgetown University. Active years: 2008-2026.
Company Filing History:
2 out of 3,690 
1 out of 498 
Years Active: 2008-2026
Title: John F Brognard: Innovator in Kinase Inhibitors
Introduction
John F Brognard is an inventor based in Middletown, MD (US). He is known for his work in the field of kinase inhibitors, which are crucial in the treatment of various diseases. Although he currently holds no granted patents, his contributions to the field are noteworthy.
Latest Patent Applications
Brognard's latest patent applications include two significant innovations. The first is titled "MIXED LINEAGE KINASE INHIBITORS AND METHODS OF USE." This application discloses compounds that inhibit kinase activity and may be used to treat diseases characterized by the overexpression of mixed lineage kinases (MLKs). The compounds have a specific structure, which may include stereoisomers, tautomers, or pharmaceutically acceptable salts.
The second application is "LZK-TARGETING DEGRADERS AND METHODS OF USE." This application reveals leucine zipper-bearing kinase (LZK) targeted degraders. The compounds are designed with a general formula that includes an LZK binding moiety, a linker, and an E3-ligase binding moiety. These compounds aim to inhibit LZK activity and may be used to treat conditions associated with LZK overexpression.
Conclusion
John F Brognard is making strides in the field of kinase inhibitors through his innovative patent applications. His work has the potential to impact the treatment of diseases linked to kinase overexpression significantly.