John E Wagner

Title: John E Wagner: Innovator in Stem Cell Research

Introduction

John E Wagner is a notable inventor based in Plymouth, MN (US), recognized for his contributions to the field of stem cell research. His innovative work has led to the development of a unique cell population that holds significant potential for medical applications, particularly in autologous bone marrow transplantation and gene therapy.

Latest Patents

Wagner holds a patent for a pluripotential quiescent stem cell population. This patent describes a cell population composed of cells bearing the stem cell marker CD34, which are small in size and exhibit minimal granulation. The cells are obtained by separating low-density mononuclear hematopoietic cells according to size and selecting for CD34.sup.+ cells in the smallest size fraction. The size of this cell population corresponds to that obtained at a flow rate of 25-29 ml/min in a counterflow elutriation method using a rotor equivalent to Beckman JE 5.0 spun at 900.times.g. This population consists essentially of very early progenitor cells, which are crucial for advancements in medical therapies.

Career Highlights

Throughout his career, John E Wagner has made significant strides in the field of stem cell research. He has worked with esteemed institutions, including the University of Minnesota and Rhône-Poulenc Rorer Pharmaceuticals Inc. His research has paved the way for new methodologies in stem cell applications, enhancing the understanding and utilization of these vital cells in therapeutic contexts.

Collaborations

Wagner has collaborated with various professionals in his field, including Jane S Lebkowski, to further advance the research and application of stem cell technologies.

Conclusion

John E Wagner's innovative contributions to stem cell research exemplify the impact of dedicated inventors in the medical field. His work continues to influence the future of regenerative medicine and therapeutic interventions.