John E Sheats

Title: John E. Sheats: Innovator in Ascorbate Resistant Compositions

Introduction

John E. Sheats is a notable inventor based in Princeton, NJ (US). He has made significant contributions to the field of analytical chemistry, particularly in the development of compositions and methods that enhance the detection of components in test samples.

Latest Patents

One of his key patents is focused on an ascorbate resistant composition, test device, and method for detecting components in the presence of interfering substances, such as ascorbic acid. This innovative composition includes an oxidase or other substances capable of producing peroxide in the presence of the target component. It also features a peroxidatively active substance, a chromogen that provides a detectable response, and a complex of mercuric ion with one or more ligands. The ligands are designed to bind covalently to the ion, forming a water-soluble complex that does not interfere with the detectable response.

Career Highlights

John E. Sheats has been associated with Miles Laboratories, Inc., where he has applied his expertise in developing advanced testing methods. His work has contributed to the improvement of analytical techniques used in various applications.

Collaborations

Throughout his career, John has collaborated with notable colleagues, including Thomas A. Magers and David L. Tabb. These collaborations have furthered the development of innovative solutions in the field.

Conclusion

John E. Sheats is a distinguished inventor whose work in ascorbate resistant compositions has made a significant impact in analytical chemistry. His contributions continue to influence the methods used for detecting components in complex test samples.