Company Filing History:
Years Active: 1996
Title: The Innovations of John D. Windass: A Pioneering Inventor in Immunology
Introduction: John D. Windass, based in Wokingham, GB, is a notable inventor recognized for his contributions to immunology through his innovative research and patent work. With a focus on developing novel compounds for medical applications, Windass has made significant strides in enhancing the specificity and affinity of antibodies.
Latest Patents: Windass holds a patent for an "Immunogenic ryanodine derivative and related uses." This groundbreaking patent discloses a novel photo-activatable derivative of ryanodine, specifically 9-hydroxy-21-(4-azidobenzoyloxy)-9-epiryanodine. The patent details the conjugation of this ryanodine derivative with keyhole limpet hemocyanin (KLH), leading to the production of antibodies that exhibit high affinity and specificity for ryanodine. A significant aspect of this patent is the development of a radioimmunoassay specific for ryanodine, utilizing anti-ryanodine antibodies and achieving a dissociation constant for ryanodine of 1 nM. Additionally, the binding interactions of a labeled, photoactivatable derivative of ryanodine with the ryanodine receptor in skeletal, cardiac, and brain membranes are disclosed, with findings on a critical 76 kDa tryptic fragment essential for forming the high-affinity ryanodine binding site.
Career Highlights: John D. Windass is associated with the University of Iowa Research Foundation, where he continues to pursue his research interests and innovate within the field. His commitment to advancing immunological research has led to the development of tools that could have significant implications for understanding and treating various medical conditions.
Collaborations: Windass has worked alongside distinguished colleagues such as Kevin P. Campbell and Derrick R. Witcher, contributing to a collaborative environment that fosters innovation and scientific discovery. Their joint efforts emphasize the importance of teamwork in advancing research and developing groundbreaking inventions.
Conclusion: John D. Windass’s contributions to immunology through his patent for a novel ryanodine derivative exemplify the impact of innovative research in medical science. With his ongoing work at the University of Iowa Research Foundation, Windass continues to be a driving force in the advancement of antibody development, showcasing the vital role that inventors play in shaping the future of healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.