Company Filing History:
Years Active: 1998-2000
Title: Innovations of John D Rizzo in Antiviral Research
Introduction
John D Rizzo is a notable inventor based in Downers Grove, IL, who has made significant contributions to the field of antiviral research. With a total of nine patents to his name, Rizzo has focused on developing methods for the preparation of potent HIV reverse transcriptase inhibitors. His work has the potential to impact the treatment and prevention of viral infections.
Latest Patents
Rizzo's latest patents include innovative methods for the preparation of (.+-.)-calanolide A and its analogues. One of his key inventions involves a method for preparing (.+-.)-calanolide A from chromene 4, which is a potent HIV reverse transcriptase inhibitor. This method utilizes a reaction with acetaldehyde diethyl acetal or paraldehyde in the presence of an acid catalyst, leading to the production of useful intermediates. Additionally, he has developed a method for resolving (.+-.)-calanolide A into its optically active forms, which can be achieved through a chiral HPLC system or enzymatic acylation and hydrolysis. Another significant patent focuses on the preparation of (+)-calanolide A, which also demonstrates high yield and enantiomeric purity.
Career Highlights
Rizzo is currently associated with Sarawak Medichem Pharmaceuticals, Inc., where he continues to advance his research in antiviral compounds. His work has garnered attention for its potential applications in treating viral infections, particularly those related to HIV.
Collaborations
Throughout his career, Rizzo has collaborated with notable colleagues, including Michael T Flavin and Ze-Qi Xu. These partnerships have contributed to the development of his innovative methods and have enhanced the research output in the field of antiviral drugs.
Conclusion
John D Rizzo's contributions to antiviral research through his innovative patents highlight his role as a significant inventor in the field. His work not only advances scientific knowledge but also holds promise for improving treatment options for viral infections.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.