Location History:
- Cork, IE (2012)
- Dublin, IE (2016)
Company Filing History:
Years Active: 2012-2016
Title: John Crowley: Innovator in Cell Culturing Technology
Introduction
John Crowley is a notable inventor based in Dublin, Ireland. He has made significant contributions to the field of biotechnology, particularly in the area of cell culturing processes. With a total of 2 patents to his name, Crowley has developed innovative methods that enhance the efficiency of cell culture techniques.
Latest Patents
Crowley's latest patents focus on processes for cell culturing by continuous perfusion. The first patent describes a method where cell culture medium is added to a cell culture, which is then circulated over a filter module containing hollow fibers. This results in an outflow of liquid with a lower cell density than the original culture. The flow within the filter module is characterized by alternating tangential flow. This method is particularly effective for culturing aggregating cells and allows for the production of biological substances, such as antibodies, which can be purified in downstream processing.
The second patent reiterates the same innovative process, emphasizing the importance of adding culture medium at a specific perfusion rate and removing biomass from the culture at least once. This dual focus on continuous perfusion and alternating tangential flow showcases Crowley's commitment to advancing cell culture methodologies.
Career Highlights
Throughout his career, John Crowley has worked with several prominent companies, including Dpx Holdings B.V. and DSM IP Assets B.V. His experience in these organizations has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Crowley has collaborated with notable professionals in his field, including Maike Wubben and Jose Manuel Coco Martin. These partnerships have likely enriched his work and led to further advancements in his innovative processes.
Conclusion
John Crowley is a distinguished inventor whose work in cell culturing technology has the potential to significantly impact the biotechnology industry. His innovative patents reflect a deep understanding of cell culture processes and a commitment to improving methodologies in this vital field.