Location History:
- Birmingham, AL (US) (1999 - 2009)
- Homewood, AL (US) (2023)
Company Filing History:
7 out of 636 
1 out of 260 
1 out of 832,912 Years Active: 1999-2023
Title: **The Innovative Contributions of John Christopher Kappes**
Introduction
John Christopher Kappes, an accomplished inventor based in Birmingham, Alabama, has made significant strides in the field of biotechnology. With a total of eight patents to his name, Kappes focuses on enhancing genetic therapies and improving the stability of critical proteins, showcasing his dedication to scientific advancement.
Latest Patents
Among his latest inventions is a patent for **Modified cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides with increased stability and uses thereof**. This invention targets modified CFTR proteins or fragments, which incorporate amino acid mutations aimed at enhancing structural stability. Specifically, these modified proteins differ from the wild-type human CFTR protein by exhibiting four or more mutations that increase their stability compared to their wild-type counterparts. Another notable contribution is his patent for **Trans-lentiviral vector particles and transduction of eukaryotic cells therewith**. This invention details trans-lentiviral gene transfer vectors and methodologies for transducing primary nondividing cells, with enhancements aimed at improving transduction efficiency and gene expression.
Career Highlights
Kappes has built a prominent career by working with esteemed organizations such as the UAB Research Foundation and the University of Alabama Research Foundation. His work within these institutions has allowed him to pursue groundbreaking research and has contributed to his notable patent portfolio.
Collaborations
Collaboration has played a crucial role in Kappes' endeavors. He has worked alongside skilled colleagues such as Xiaoyun Wu and Zhengrong Yang, enhancing the depth and breadth of his research projects. These partnerships have fostered an environment of innovation and creativity that drives scientific discovery.
Conclusion
In summary, John Christopher Kappes stands out as a prominent inventor whose work in biotechnology and genetic therapies significantly impacts the field. With eight patents to his name and a history of collaboration with leading institutions and fellow researchers, Kappes continues to push the boundaries of scientific innovation. His dedicated contributions to the understanding and treatment of genetic conditions mark him as a key figure in modern scientific advancements.