Company Filing History:
Years Active: 2019
Title: John C. Rutledge: Innovator in Single-Cell Raman Spectroscopy
Introduction
John C. Rutledge is a prominent inventor based in Davis, CA (US). He has made significant contributions to the field of spectroscopy, particularly in the analysis of cells and cellular components. His innovative approach has paved the way for advancements in non-destructive and non-invasive techniques.
Latest Patents
Rutledge holds a patent for "Single-cell Raman spectroscopy for the non-destructive, non-invasive analysis of cells and cellular components." This patent describes a method for obtaining Raman spectra of various cells, including normal human T- and B-cells from peripheral blood or human tonsil, as well as their transformed counterparts. The technique involves optically trapping the cells and analyzing their Raman spectra using multiple excitation wavelengths. The ability to subtract spectra to create difference spectra and apply Principal Component Analysis (PCA) enhances the characterization of the trapped cells.
Career Highlights
John C. Rutledge is associated with Lawrence Livermore National Security, LLC, where he continues to contribute to innovative research and development. His work has implications for various fields, including medical diagnostics and cellular biology.
Collaborations
Some of his notable coworkers include James W. Chan and Thomas R. Huser, who have collaborated with Rutledge on various projects, further enriching the research environment.
Conclusion
John C. Rutledge's contributions to single-cell Raman spectroscopy exemplify the impact of innovative thinking in scientific research. His work not only advances the field but also opens new avenues for future exploration and application.