John C Prescott

Title: John C Prescott: Innovator in Protein Kinase Inhibitors

Introduction

John C Prescott is a notable inventor based in San Francisco, CA (US). He has made significant contributions to the field of biochemistry, particularly in the identification of protein kinase inhibitors. With a total of 2 patents, Prescott's work has the potential to impact therapeutic strategies in various diseases.

Latest Patents

Prescott's latest patents include innovative methods for identifying kinase inhibitors. The first patent focuses on the identification of protein kinase inhibitors that preferentially bind to the inactive conformation of a target protein kinase. This invention utilizes a covalent tethering approach to lock the target protein kinase in an inactive state, allowing for the identification of inhibitors that specifically target this conformation. The second patent presents an extended tethering approach for the rapid identification of ligands. This method enhances the identification and characterization of binding partners for a target molecule, improving binding affinity through an improved tethering technique.

Career Highlights

John C Prescott is currently associated with Sunesis Pharmaceuticals, Inc., where he continues to advance his research in the field of biochemistry. His work is instrumental in developing new therapeutic options that could lead to better treatment outcomes for patients.

Collaborations

Prescott has collaborated with notable colleagues, including Andrew Braisted and Daniel A Erlanson. These collaborations have fostered a productive research environment, contributing to the advancement of their shared goals in the field.

Conclusion

John C Prescott's innovative work in the identification of protein kinase inhibitors showcases his commitment to advancing biochemistry and therapeutic development. His contributions are paving the way for future breakthroughs in medical science.