John C Mauck

Title: The Innovations of John C Mauck

Introduction

John C Mauck is a notable inventor based in Rochester, NY, with a remarkable portfolio of 17 patents. His work primarily focuses on analytical elements that enhance the detection and quantification of various substances in biological fluids. His innovative approaches have significantly contributed to the fields of medical diagnostics and analytical chemistry.

Latest Patents

One of his latest patents is the "Dry analytical element for acetaminophen assay." This invention involves a spectrophotometric assay designed for the detection of acetaminophen in aqueous fluids. The dry analytical element consists of a support with one or more reagent layers that include a first enzyme, aryl acylamidase, which cleaves the amide bond of acetaminophen to produce p-aminophenol. A mild oxidizing agent is then used to oxidize the p-aminophenol, allowing it to couple with a water-soluble coupling agent to form a dye that can be read at 670 nm. This assay is known for its precision and accuracy on serum and plasma samples, while also being relatively free from significant interferences. Additionally, it allows for measurement over a broad dynamic range.

Another significant patent is the "Dry analytical elements for the determination of protein." This invention provides a method for the sensitive and rapid detection and quantification of protein. The assay utilizes a dye that reacts with protein and molybdate ion, resulting in a measurable change in the spectral absorption of the dye. The patent also includes polymers that stabilize and enhance the accuracy of the assay, as well as compounds that reduce interference from bicarbonate.

Career Highlights

Throughout his career, John C Mauck has worked with prominent companies such as Eastman Kodak Company and Ortho Clinical Diagnostics, Inc. His contributions to these organizations have been instrumental in advancing diagnostic technologies.

Collaborations

John has collaborated with notable individuals in his field, including Harold C Warren and David B LaTart. These partnerships have fostered innovation and have led to the development of groundbreaking technologies in analytical chemistry.

Conclusion

John C Mauck's contributions to the field of analytical diagnostics through his numerous patents and collaborations highlight his significant impact on medical technology. His innovative work continues to influence the way substances are detected and quantified in biological samples.