San Diego, CA, United States of America

John C Mathison


Average Co-Inventor Count = 4.4

ph-index = 5

Forward Citations = 48(Granted Patents)


Company Filing History:


Years Active: 1998-2008

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7 patents (USPTO):Explore Patents

Title: Innovations of John C Mathison

Introduction

John C Mathison is a notable inventor based in San Diego, CA. He has made significant contributions to the field of biotechnology, particularly in the development of monoclonal antibodies. With a total of seven patents to his name, Mathison's work has the potential to impact medical treatments significantly.

Latest Patents

One of Mathison's latest patents is focused on hybrid cells producing monoclonal anti-CD14 antibodies. This invention provides hybridoma cell lines that produce monoclonal antibodies which inhibit CD14 mediated cell activation. The monoclonal antibodies produced by these cell lines are useful for detecting the presence of cell surface and soluble CD14 in a sample. Additionally, chimeric and CDR grafted antibodies generated from these monoclonal antibodies are also provided. Pharmaceutical compositions containing these biological compositions are designed to treat and prevent disorders associated with CD14 mediated cell activation, such as sepsis. Another significant patent involves methods and compositions for ameliorating the symptoms of sepsis. This invention concerns a method of treating sepsis by administering a therapeutically effective amount of anti-CD14 antibody molecules. A therapeutic composition comprising anti-CD14 antibody molecules in a pharmaceutically acceptable excipient is also contemplated.

Career Highlights

Throughout his career, John C Mathison has worked with prestigious organizations, including The Scripps Research Institute. His work has been instrumental in advancing the understanding and treatment of various medical conditions.

Collaborations

Mathison has collaborated with notable individuals in his field, including Richard J Ulevitch and Peter S Tobias. These collaborations have further enriched his research and innovations.

Conclusion

John C Mathison's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the medical field. His work continues to pave the way for advancements in treatments for serious health conditions.

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