This inventor holds 6 USPTO granted patents. Top assignee: The Dow Chemical Company. Active years: 1981-1991.
Location History:
- Danville, CA (US) (1981)
- Concord, CA (US) (1986 - 1989)
- Lafayette, CA (US) (1990 - 1991)
Company Filing History:
5 out of 7,680 
Years Active: 1981-1991
Title: John C Little: Innovator in Chemical Synthesis
Introduction
John C Little is a notable inventor based in Lafayette, CA (US). He has made significant contributions to the field of chemical synthesis, holding a total of 6 patents. His work has advanced the understanding and application of various chemical compounds.
Latest Patents
One of John C Little's latest patents involves the preparation of 2,3-difluoro-5-(trifluoromethyl)pyridine. This compound is synthesized by contacting a 2,3-dihalo-5-(trifluoromethyl)pyridine with an effective amount of KF or CsF in a polar aprotic solvent at elevated temperatures under substantially anhydrous conditions. The process includes the removal of the difluoropyridine products as they are formed, and the starting material may be added during the reaction to minimize decomposition. Additionally, the reaction can be conducted in the presence of an acid scavenger and/or a crown ether or other phase-transfer catalyst.
Career Highlights
John C Little is associated with The Dow Chemical Company, where he has been instrumental in various innovative projects. His expertise in chemical synthesis has led to advancements that benefit both the company and the broader scientific community.
Collaborations
Throughout his career, John has collaborated with esteemed colleagues such as Charles A Wilson and George S Fujioka. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
John C Little's contributions to chemical synthesis and his innovative patents highlight his role as a significant figure in the field. His work continues to influence advancements in chemical research and applications.