John C Hunter

Title: John C. Hunter: Inventor in RNAi-Based Pain Research

Introduction

John C. Hunter is an inventor associated with Warren, New Jersey. His patent work includes inventions involving short interfering nucleic acids and the NaV1.8 sodium channel, a target relevant to pain research. Hunter is credited with 4 patents.

Latest Patents

The supplied descriptions for Hunter’s latest patents cover short interfering nucleic acids, in single-stranded or double-stranded forms, designed to trigger RNA interference and degrade messenger RNA from the NaV1.8 sodium channel gene. The inventions also describe pharmaceutical compositions and recombinant vectors containing these nucleic acids.

The described methods include inhibiting messenger RNA translation and polypeptide expression, blocking membrane potential or sodium current in a cell, and inhibiting chronic pain. The two patent descriptions provided are identical, so separate patent titles or details cannot be identified from the supplied information.

Career Highlights

Hunter’s listed company affiliations include Schering Corporation and Merck Sharp & Dohme Corp. The supplied patent descriptions connect his work with nucleic-acid-based approaches to modulating sodium-channel activity and investigating potential applications in chronic pain.

Collaborations

Hunter’s listed coworkers include Tony Priestley and Sameer Goregaoker. The information provided does not specify their roles or identify particular patents they worked on together.

Conclusion

John C. Hunter’s reported patent portfolio highlights research into RNA interference, the NaV1.8 sodium channel, and potential methods for addressing chronic pain.