Company Filing History:
Years Active: 2018
Title: Innovations of John Bardsley in Biomass Conversion
Introduction
John Bardsley is an accomplished inventor based in Cambridge, MA (US). He has made significant contributions to the field of biomass conversion, particularly in the development of thermophilic organisms for ethanol production. His innovative work focuses on utilizing mutant strains of thermophilic organisms to enhance the efficiency of converting lignocellulosic biomass into ethanol.
Latest Patents
John Bardsley holds a patent for "Thermophilic organisms for conversion of lignocellulosic biomass to ethanol." This patent describes mutant thermophilic organisms that can consume a variety of biomass-derived substrates. The strains disclosed in the patent have eliminated the expression of acetate kinase and phosphotransacetylase. Notably, strain ALK1 has been engineered through site-directed homologous recombination to knockout both acetic acid and lactic acid production. Continuous culture involving substrate concentration challenges led to the evolution of ALK1, resulting in a more robust strain designated ALK2. These organisms can be utilized in thermophilic SSF and SSCF reactions performed at optimal temperatures for cellulase activity, producing near-theoretical ethanol yields without expressing pyruvate decarboxylase.
Career Highlights
John Bardsley is affiliated with Dartmouth College, where he continues to advance research in biomass conversion technologies. His work has garnered attention for its potential to improve the sustainability of biofuel production.
Collaborations
Some of his notable coworkers include Arthur J Shaw, Iv, and Sunil G Desai. Their collaborative efforts contribute to the ongoing research and development in the field of thermophilic organisms and biomass conversion.
Conclusion
John Bardsley's innovative work in the field of biomass conversion exemplifies the potential of thermophilic organisms in sustainable ethanol production. His contributions are paving the way for advancements in biofuel technologies.