This inventor holds 3 USPTO granted patents. Top assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New Jersey. Active years: 1991-1997.
Company Filing History:
3 out of 1,492 
1 out of 272 
Years Active: 1991-1997
Title: Innovations by John B Kostis in Noninvasive Cardiac Diagnostics
Introduction
John B Kostis is a notable inventor based in Warren, NJ (US), recognized for his contributions to the field of noninvasive cardiac diagnostics. He holds a total of 3 patents, which focus on innovative methods for detecting coronary artery disease. His work has significantly advanced the understanding and diagnosis of heart conditions, making it easier for healthcare professionals to assess patients without invasive procedures.
Latest Patents
Kostis's latest patents include a "System and method for noninvasive detection of arterial stenosis" and a "Noninvasive diagnostic system for coronary artery disease." The first patent describes a system that utilizes a vasodilator drug to enhance the signal-to-noise ratio of acoustic signals representing diastolic heart sounds. This system employs a wavelet transform to create a feature vector that incorporates various clinical parameters, which are then analyzed using neural networks to diagnose coronary stenosis.
The second patent outlines a method for analyzing diastolic heart sounds to identify auditory components associated with turbulent blood flow in partially occluded coronary arteries. This system employs advanced signal processing techniques, including Autoregressive (AR) and Autoregressive Moving Averaging (ARMA) methods, to reliably indicate the presence of these components even in noisy environments. The system is designed for minimal operator interaction, featuring an acoustic transducer and a controller for automatic data collection and analysis.
Career Highlights
Throughout his career, John B Kostis has worked with prestigious institutions such as Rutgers, the State University of New Jersey, and the University of Medicine and Dentistry of New Jersey. His work has been instrumental in bridging the gap between advanced technology and practical medical applications, particularly in the realm of cardiac health.
Collaborations
Kostis has collaborated with notable professionals in his field, including Walter Welkowitz and John Leonard Semmlow. These collaborations have further enriched his research and development efforts, leading to innovative solutions in noninvasive diagnostics.
Conclusion
John B Kostis's contributions to noninvasive cardiac diagnostics exemplify the impact of innovation in healthcare. His patents and collaborative efforts continue to pave the way for advancements in the detection and treatment of coronary artery disease.