Arcadia, CA, United States of America

John A Zaia

USPTO Granted Patents = 12 

Average Co-Inventor Count = 2.9

ph-index = 7

Forward Citations = 211(Granted Patents)


Company Filing History:


Years Active: 1991-2012

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12 patents (USPTO):Explore Patents

Title: Innovations by John A. Zaia: A Trailblazer in Viral RNA Detection and Immunotherapy

Introduction

John A. Zaia, based in Arcadia, California, is a prolific inventor known for his significant contributions to the fields of viral detection and immunology. With a remarkable portfolio consisting of 12 patents, Zaia focuses on innovating methods that enhance the detection of viral RNA sequences and developing effective immunotherapies.

Latest Patents

Zaia's latest patents showcase his expertise and commitment to advancing medical science. One notable invention is the "Method for amplification and detection of RNA sequences," which is a groundbreaking process for identifying viral RNA nucleotide sequences present in samples of peripheral blood cells. This process involves amplifying the RNA simultaneously with at least one other RNA sequence in virus-infected cells and analyzing the resulting products with specific probes.

Another significant patent is related to "Protein kinase deficient, immunologically active CMVpp65 mutants." This invention focuses on mutated CMVpp65, a viral structural protein that activates cell-mediated immunity in humans infected with Cytomegalovirus (CMV). The transformative mutations eliminate the undesired protein kinase activity, paving the way for the production of both DNA and protein vaccines. This innovation offers a range of applications, including methods to enhance immune responses and gene therapy vectors for CMV vaccination.

Career Highlights

Throughout his career, John A. Zaia has made substantial strides in medical research and development. His work at City of Hope, among other institutions, has contributed to a deeper understanding of viral infections and immune responses. Zaia’s dedication to his field is evident through his patents and ongoing research efforts.

Collaborations

Zaia has collaborated with renowned scientists such as John J. Rossi and Hema Pande. These partnerships exemplify his ability to work with other experts in the field, further enhancing the impact of his innovations.

Conclusion

John A. Zaia stands out as an influential figure in the realm of viral detection and immunotherapy. His patents reflect a commitment to advancing the medical field, particularly in combating viral infections through innovative technologies. As research continues to evolve, Zaia's contributions are likely to play a pivotal role in developing effective medical solutions for public health challenges.

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