Location History:
- Palo Alto, CA (US) (2000)
- Fremont, CA (US) (1998 - 2003)
Company Filing History:
Years Active: 1998-2003
Title: Johanna Olweus: Innovating Hematopoietic Progenitor Cell Research
Introduction
Johanna Olweus is a distinguished inventor based in Fremont, CA, known for her significant contributions to the field of hematopoietic progenitor cell research. With a remarkable portfolio that includes three patents, her work has impacted the understanding and identification of various progenitor cell populations, paving the way for advancements in therapeutic applications.
Latest Patents
Olweus's latest patents focus on methods to distinguish different types of hematopoietic progenitor cells. The first patent details a method examining the expression of various cell adhesion molecules and growth factor receptors on human progenitor cells, specifically those marked as CD34 and CD38. The discovery shows that alterations in these expressions correlate with the cell's progression toward specific lineages. This innovative approach allows for the identification and isolation of distinct progenitor cell populations using multiple markers.
Another significant patent revolves around the differentiation of granulocytic and monocytic progenitor cells. This invention highlights how M-CSF responsiveness and M-CSFR expression can effectively distinguish between monocytic and granulocytic cells from CD34 high-expressing cells. By isolating phenotypically defined CD34+ subsets and utilizing anti-M-CSFR monoclonal antibodies for measurement, Olweus reveals critical insights into the lineage commitment of these progenitor cells, which is crucial for understanding their developmental pathways.
Career Highlights
Johanna Olweus has established her career at Becton Dickinson and Company, where her research and inventions continue to shape the landscape of hematology and cell biology. With her innovative methodologies, she has the potential to influence therapeutic strategies for various blood-related disorders, enhancing the prospects for future medical advancements.
Collaborations
Throughout her career, Olweus has collaborated with notable colleagues such as Fridtjof Lund-Johansen and Leon W. Terstappen. These collaborations have enriched her research endeavors, allowing for a multidisciplinary approach that has ultimately contributed to the success of her projects and patents.
Conclusion
Johanna Olweus stands out as a pioneering inventor in the realm of hematopoietic progenitor cell research. With three patents to her name, her contributions reflect a commitment to innovation and scientific excellence. Her ongoing work at Becton Dickinson and her collaborations with esteemed colleagues affirm her status as a leading figure in her field, with the potential to advance our understanding of cell biology significantly.