The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 1998

Filed:

May. 14, 1997
Applicant:
Inventors:

Leon W Terstappen, Huntingdon Valley, PA (US);

Michael R Loken, Mercer Island, WA (US);

Shiang Huang, San Ramon, CA (US);

Johanna Olweus, Fremont, CA (US);

Fridtjof Lund-Johansen, Fremont, CA (US);

Assignee:

Becton Dickinson and Company, Franklin Lakes, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435372 ; 424 931 ; 435325 ; 435326 ;
Abstract

One or more population of cells enriched for human hematopoietic stem cells is disclosed. HSC in this population of cells are capable of limited self-renewal and are capable of differentiating into all elements of the hematopoietic system. This population of cells has the phenotype of CD34.sup.+ /CD38.sup.- and more preferably CD34.sup.+ /CD38.sup.- /HLA-DR.sup.+. Cells within this population have been found to express CD13, CD33 and CD71. Hematopoietic stem cells can be used in a number of therapies, including autologous transplantation and in gene therapy.


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