Company Filing History:
Years Active: 2009-2012
Title: Johanna Kölln: Innovator in Complement Modulation
Introduction
Johanna Kölln is a prominent inventor based in Hamburg, Germany. She has made significant contributions to the field of complement modulation, with a focus on developing innovative polypeptides that enhance complement depleting properties. Her work has led to the filing of two patents, showcasing her expertise and dedication to advancing medical science.
Latest Patents
Johanna Kölln's latest patents include groundbreaking inventions related to complement depletion using recombinant human C-3 derivatives. The first patent provides isolated polypeptides that exhibit complement-modulating activity. These polypeptides are designed to efficiently consume complement in human serum, significantly improving the half-life of C3 convertases. The current invention offers human C3 derivatives capable of forming C3 convertases with an extended CVF, Bb-like half-life of several hours, compared to the natural C3 convertases that last only 1.5 minutes. This innovation allows for a more effective therapeutic approach by escaping physiological degradation mechanisms.
Career Highlights
Johanna Kölln is associated with Pls-design GmbH, where she continues to push the boundaries of research in her field. Her work has garnered attention for its potential applications in medical treatments and therapies.
Collaborations
Throughout her career, Johanna has collaborated with notable colleagues, including Edzard Spillner and Reinhard Bredehorst. These partnerships have enriched her research and contributed to the success of her innovative projects.
Conclusion
Johanna Kölln stands out as a leading inventor in the realm of complement modulation, with her patents reflecting her commitment to advancing medical science. Her contributions are poised to make a significant impact in the field, paving the way for future innovations.