New York, NY, United States of America

Jochen Buck



Average Co-Inventor Count = 3.8

ph-index = 7

Forward Citations = 100(Granted Patents)


Company Filing History:


Years Active: 1994-2002

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17 patents (USPTO):Explore Patents

Title: Jochen Buck: Innovator in Hematopoietic Research

Introduction

Jochen Buck is a prominent inventor based in New York, NY (US), known for his significant contributions to the field of hematopoietic research. With a total of 17 patents to his name, he has made remarkable advancements in the understanding and treatment of blood cell expansion and related therapies.

Latest Patents

One of Jochen Buck's latest patents is a c-kit ligand-based method for expanding peripheral blood cell levels. This pharmaceutical composition includes the c-kit ligand (KL), which can be purified or produced through recombinant methods. The invention outlines methods for treating patients by administering this composition, which combines KL with other hematopoietic factors and a pharmaceutically acceptable carrier. Additionally, it provides combination therapies using KL and a purified KL polypeptide, or a soluble fragment thereof, along with other hematopoietic factors. The patent also describes methods and compositions for ex-vivo use of KL, as well as a mutated KL antagonist, which may be a small molecule. Furthermore, it discusses the use of antisense nucleic acids to KL as therapeutics and highlights the role of KL in germ cells, mast cells, and melanocytes.

Career Highlights

Throughout his career, Jochen Buck has worked with esteemed institutions such as the Sloan Kettering Institute for Cancer Research and Columbia University. His work has significantly impacted the field of hematology and has paved the way for new therapeutic approaches.

Collaborations

Jochen has collaborated with notable colleagues, including Fadila Derguini and Koji Nakanishi, contributing to various research projects and innovations in his field.

Conclusion

Jochen Buck's innovative work in hematopoietic research and his numerous patents reflect his dedication to advancing medical science. His contributions continue to influence the development of new therapies for blood-related conditions.

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