Company Filing History:
Years Active: 2004-2006
Title: Joanne Lightowler: Innovator in Enzymatic Activity Modulation
Introduction
Joanne Lightowler is a prominent inventor based in York, GB. She has made significant contributions to the field of enzymatic activity modulation, holding a total of 3 patents. Her innovative work focuses on developing methods and compositions that enhance the understanding and application of enzymatic processes.
Latest Patents
Lightowler's latest patents include groundbreaking inventions. One of her notable patents is titled "Compositions and methods for screening for modulators of enzymatic activity." This invention provides a method to screen for a modulator of enzymatic activity by monitoring the association or dissociation of a pair of polypeptides that can associate as a dimer. The polypeptide pair consists of a first polypeptide with detection means and a site of post-translational modification, along with a second polypeptide that also includes detection means.
Another significant patent is "Methods and compositions using coiled binding partners." This invention relates to a polypeptide multimer that includes a first polypeptide associated with a label and a second polypeptide. Key features of this invention include the susceptibility of at least one polypeptide to protease digestion, the detectability of the multimer's association via a signal emitted by the label, and the modulation of the signal upon digestion of at least one polypeptide, which results in the dissociation of the multimer.
Career Highlights
Joanne Lightowler is currently associated with Cyclacel Limited, where she continues to advance her research and innovations. Her work has been instrumental in enhancing the understanding of enzymatic activities and their applications in various fields.
Collaborations
Throughout her career, Lightowler has collaborated with notable colleagues, including John Colyer and Derek N Woolfson. These collaborations have contributed to her success and the advancement of her research.
Conclusion
Joanne Lightowler is a distinguished inventor whose work in enzymatic activity modulation has led to significant advancements in the field. Her innovative patents and collaborations reflect her commitment to scientific progress and innovation.