Location History:
- Derry, NH (US) (2010 - 2012)
- Litchfield, NH (US) (2012 - 2022)
Company Filing History:
Years Active: 2010-2022
Title: Innovations in Cancer Detection: The Patented Work of Joan MacNeill
Introduction: Joan MacNeill, an accomplished inventor based in Litchfield, NH, has made significant contributions to the field of cancer research, particularly in the detection of mutant anaplastic lymphoma kinase (ALK) linked to lung cancer. With a total of 12 patents to her name, MacNeill has positioned herself as a leading innovator in biochemistry and molecular diagnostics.
Latest Patents: Joan MacNeill's most recent patents revolve around groundbreaking methods and compositions for detecting mutant anaplastic lymphoma kinase in lung cancer. Her innovative work identifies novel gene deletions and translocations involving chromosome 2, leading to the discovery of fusion proteins that combine parts of the ALK kinase with secondary proteins such as Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein has been shown to stimulate the proliferation and survival of non-small cell lung carcinoma (NSCLC) cells characterized by this specific mutation. Her inventions encompass isolated polynucleotides, vectors encoding mutant ALK kinase polypeptides, probes for detection, and reagents for identifying fusion and truncated polypeptides. Additionally, MacNeill's patents offer methods for screening compounds to inhibit these proteins, providing a pathway for cancer treatment advancements.
Career Highlights: Over her career, Joan MacNeill has distinguished herself through her relentless pursuit of innovation in the life sciences. Her work at Cell Signaling Technology, Inc. reflects her commitment to advancing molecular diagnostics and cancer therapies. With a solid foundation in biochemistry, MacNeill has applied her expertise to create patented technologies that not only enhance detection methods but also pave the way for targeted treatments in oncology.
Collaborations: Throughout her journey, Joan MacNeill has collaborated with notable peers, such as Klarisa Rikova and Herbert Haack. These partnerships have fostered an environment of creativity and innovation, allowing for the exchange of ideas and collective advancements in their field, enhancing the quality and impact of their work on cancer research.
Conclusion: Joan MacNeill's contributions to the detection of mutant ALK kinase in lung cancer exemplify the vital role of innovation in healthcare. Her patents not only provide tools for diagnosing cancer more effectively but also open avenues for developing targeted therapies. As an inventor, MacNeill continues to inspire the next generation of scientists and researchers aiming to make meaningful impacts in the fight against cancer. Her work serves as a testament to the importance of innovation and collaboration in improving patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.