Company Filing History:
Years Active: 1999-2000
Title: Joan A. Kobori: Innovator in Cell Selection Technologies
Introduction
Joan A. Kobori is a notable inventor based in Pasadena, CA, recognized for her contributions to the field of cell selection technologies. With a total of 2 patents, her work focuses on innovative methods for the release and selection of specific cell types, which have significant implications in medical treatments.
Latest Patents
Kobori's latest patents include groundbreaking inventions related to positive and positive/negative cell selection mediated by peptide release. The first patent describes a non-enzymatic method for releasing cells that have been selected from a heterogeneous cell suspension through antibody-mediated binding to solid supports. This method involves forming a complex with a primary monoclonal antibody linked to a solid support, which binds to a cell surface antigen on target cells. The complex is then separated from the suspension and treated with a specific peptide that displaces the antibody, effectively releasing the target cell. The second patent similarly outlines methods for positive/negative cell selection, emphasizing the purification of CD34+ hematopoietic stem cells while purging undesired tumor cells or lymphocytes. This purified cell composition is crucial for reinfusing cancer patients after high-dose therapy to help reconstitute their immune systems.
Career Highlights
Joan A. Kobori has made significant strides in her career, particularly through her role at Nexell Therapeutics Inc. Her innovative approaches to cell selection have positioned her as a leader in the field, contributing to advancements in therapeutic applications.
Collaborations
Kobori has collaborated with esteemed colleagues, including Janet Tseng-Law and Fahad A. Al-Abdaly, further enhancing the impact of her work in the scientific community.
Conclusion
Joan A. Kobori's innovative contributions to cell selection technologies demonstrate her commitment to advancing medical science. Her patents not only reflect her expertise but also hold the potential to improve patient outcomes in cancer treatment.