Jiye Shi

Title: Jiye Shi: Innovator in Therapeutic Ligand Design

Introduction

Jiye Shi is a notable inventor based in Brussels, Belgium. He has made significant contributions to the field of therapeutic ligand design, focusing on methods that enhance the binding affinity of ligands to macromolecular targets. His innovative approach utilizes advanced computational techniques to improve therapeutic outcomes.

Latest Patents

Jiye Shi holds a patent for "Obtaining an improved therapeutic ligand." This patent involves methods and associated apparatus for designing a ligand ab initio that binds to a binding site of a macromolecular target. The process includes identifying modifications to a ligand to improve its affinity, using information about non-bonding, intra-molecular, or inter-molecular atom-to-atom contacts extracted from a database of biological macromolecules. The goal is to identify favored regions adjacent to the binding site for specific atom types and modify a candidate ligand to enhance the intersection between the ligand's atoms and these favored regions. Notably, one or more steps of the methods may be performed by a computer. Jiye Shi has 1 patent to his name.

Career Highlights

Jiye Shi is currently employed at UCB Biopharma Srl, where he continues to advance his research in therapeutic ligands. His work is characterized by a strong emphasis on innovation and practical applications in the pharmaceutical industry.

Collaborations

Jiye Shi collaborates with esteemed colleagues, including Terence Seward Baker and Alastair David Griffiths Lawson. Their combined expertise contributes to the success of their projects and enhances the research environment at UCB Biopharma Srl.

Conclusion

Jiye Shi's contributions to the field of therapeutic ligand design exemplify the impact of innovative thinking in biotechnology. His patent and ongoing research efforts are paving the way for advancements in therapeutic applications.