This inventor holds 1 USPTO granted patent. Top assignee: Industrial Technology Research Institute. Active years: 1994.
Company Filing History:
Years Active: 1994
Title: Innovations of Jinun B Yeh in Cephalosporanic Acid Synthesis
Introduction
Jinun B Yeh is a notable inventor based in Hsinchu, Taiwan. He has made significant contributions to the field of pharmaceuticals, particularly in the synthesis of cephalosporanic acid. His innovative methods have the potential to enhance the efficiency of antibiotic production.
Latest Patents
Jinun B Yeh holds a patent for a method titled "Method for the preparation of .DELTA..sup.3 -7-substituted amino." This patent describes a process for synthesizing .DELTA..sup.3 -7-substituted amino desacetoxy cephalosporanic acid from a penicillin sulfoxide or its alkylsilylated ester derivative. The method involves heating penicillin sulfoxide in the presence of an organic ammonium salt catalyst and a copolymer composed of dimethylsilane and urea units. This innovative approach leads to the formation of cephalosporanic acid through a ring expansion reaction. The copolymer serves as both a dehydrating agent and an esterifying agent, resulting in high yields of cephalosporanic acid while minimizing the need for excess dimethylsilyating agents.
Career Highlights
Jinun B Yeh is affiliated with the Industrial Technology Research Institute, where he continues to advance research in pharmaceutical innovations. His work has garnered attention for its practical applications in the medical field.
Collaborations
He has collaborated with notable colleagues, including Lain-Tze Lee and Mei-Hueih Chen, contributing to a dynamic research environment that fosters innovation.
Conclusion
Jinun B Yeh's contributions to the synthesis of cephalosporanic acid exemplify the impact of innovative methods in pharmaceutical research. His work not only enhances production efficiency but also paves the way for future advancements in antibiotic development.