Jinhuan Wei

Title: Innovations of Jinhuan Wei in Peptide Compounds

Introduction

Jinhuan Wei is a notable inventor based in Jiangsu, China. He has made significant contributions to the field of peptide compounds, particularly in targeting the PD-1 receptor. His work has implications for the development of analgesic drugs, showcasing his innovative approach to addressing pain management.

Latest Patents

Jinhuan Wei holds a patent for "Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof." This patent includes a peptide compound that consists of five distinct compounds, each with amino acid sequences identical to SEQ ID NO: 1-5. The method for preparing these peptide compounds involves a solid-phase synthesis method, which allows for the sequential coupling of amino acids to a solid-phase resin. The resulting target compound is obtained through cleavage by a cutting reagent, followed by freeze-drying and preparative purification. The compounds are designed to bind to the PD-1 receptor and demonstrate significant inhibitory effects on inflammatory and visceral pain when administered intrathecally. They are noted for their simplicity in synthesis, ease of purification, and suitability for large-scale production.

Career Highlights

Jinhuan Wei is affiliated with Nantong University, where he continues to advance his research in peptide compounds. His innovative work has positioned him as a key figure in the field of medicinal chemistry, particularly in the development of new therapeutic agents.

Collaborations

Jinhuan Wei has collaborated with notable colleagues, including Gang Chen and Long Zhao. Their combined expertise contributes to the advancement of research in peptide compounds and their applications in pain management.

Conclusion

Jinhuan Wei's contributions to the field of peptide compounds targeting the PD-1 receptor highlight his innovative spirit and dedication to advancing medical science. His work not only enhances our understanding of pain management but also paves the way for future developments in therapeutic applications.