Company Filing History:
Years Active: 1997-2002
Title: The Innovative Contributions of Jimmy X Tang
Introduction
Jimmy X Tang is a notable inventor based in Framingham, MA (US). He has made significant contributions to the field of nucleic acid synthesis, holding a total of 3 patents. His work focuses on developing efficient methods and reagents for oligonucleotide synthesis, which are crucial in various biotechnological applications.
Latest Patents
One of his latest patents is titled "Polymer supports for nucleic acid synthesis." This invention provides passivated organic polymer supports, processes for their preparation, and processes for their use in oligonucleotide synthesis. These advancements allow for highly efficient solid-phase synthesis of oligonucleotides. Another significant patent is "Sulfur transfer reagents for oligonucleotide synthesis." In this research, two commercially available compounds, 3-amino-1,2,4-dithiazole-5-thione and xanthane hydride, along with their derivatives, were identified as potential sulfur-transfer reagents. The efficiency and optimization of these new sulfur-transfer reagents were investigated through solid-phase syntheses of dinucleotide and oligonucleotide phosphorothioates. The results demonstrated that both compounds exhibit high efficiency, achieving better than 99% sulfur transfer efficiency at each step. These novel sulfur-transfer reagents are stable in various solvents and are available in bulk quantities at low cost, making them viable alternatives to traditional reagents.
Career Highlights
Throughout his career, Jimmy X Tang has worked with prominent companies in the biotechnology sector, including Hybridon, Inc. and Avecia Biotechnology, Inc. His experience in these organizations has contributed to his expertise in nucleic acid synthesis and the development of innovative reagents.
Collaborations
Jimmy has collaborated with notable coworkers such as Jin-Yan Tang and Yongxin Han. Their combined efforts have further advanced the research and development of efficient methods in the field.
Conclusion
Jimmy X Tang's contributions to nucleic acid synthesis through his innovative patents and collaborations highlight his significant role in advancing biotechnology. His work continues to influence the field and pave the way for future developments.