Midlothian, United Kingdom

Jim McWhir


Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 8(Granted Patents)


Company Filing History:


Years Active: 2005

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1 patent (USPTO):Explore Patents

Title: Jim McWhir: Innovator in Stem Cell Research

Introduction

Jim McWhir is a notable inventor based in Midlothian, GB. He has made significant contributions to the field of stem cell research, particularly through his innovative patent that focuses on the selective targeting of undifferentiated stem cells. His work has implications for tissue regeneration and drug screening, showcasing the potential of stem cell technology in various applications.

Latest Patents

Jim McWhir holds a patent for "Selective antibody targeting of undifferentiated stem cells." This invention provides a system for producing differentiated cells from a stem cell population, which is essential when a relatively homogenous cell population is desirable. The cells produced contain an effector gene controlled by a transcriptional control element, such as the TERT promoter, which ensures expression in undifferentiated cells. The expression of this effector gene leads to the production of a cell-surface antigen that can be utilized to deplete undifferentiated cells. The model effector sequences encode glycosyl transferases that synthesize carbohydrate xenoantigens or alloantigens, which can be used for immunoseparation or as targets for complement-mediated lysis. The differentiated cell populations generated through this process are suitable for tissue regeneration and non-therapeutic applications, including drug screening.

Career Highlights

Throughout his career, Jim McWhir has worked with esteemed organizations such as the Roslin Institute in Edinburgh and Geron Corporation. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research in stem cell technology.

Collaborations

Some of Jim McWhir's notable coworkers include Joseph D. Gold and J. Michael Schiff. Their collaborative efforts have further advanced the understanding and application of stem cell research.

Conclusion

Jim McWhir's innovative work in the field of stem cell research, particularly through his patent on selective antibody targeting, has paved the way for advancements in tissue regeneration and drug screening. His contributions continue to influence the scientific community and hold promise for future developments in regenerative medicine.

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