Location History:
- Belmont, CA (US) (2005 - 2007)
- Princeton, NJ (US) (2007)
- South San Francisco, CA (US) (2010)
Company Filing History:
Years Active: 2005-2010
Title: The Innovative Contributions of Jill Rillema
Introduction
Jill Rillema is a prominent inventor based in Belmont, CA (US). She has made significant contributions to the field of biotechnology, particularly in the area of gene identification and therapeutic development. With a total of 4 patents to her name, Rillema's work has the potential to impact various medical applications.
Latest Patents
One of her latest patents involves the identification and cloning of a novel human gene, RET16, which plays a crucial role in the intracellular signaling cascade. This invention describes a newly discovered polynucleotide encoding a protein involved in cell signaling, specifically RET16, which has been cloned, isolated, and identified from TNF-alpha stimulated human microvascular endothelial cells. The patent also details the RET16 polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide. Furthermore, methods for screening modulators, particularly inhibitors of the human RET16 protein, are described, along with the use of the RET16 polynucleotide and polypeptide for therapeutics and diagnostics.
Another significant patent focuses on polynucleotides encoding humanized antibodies against human 4-1BB. This humanized antibody binds to human 4-1BB, facilitating its interaction with the human 4-1BB ligand. The patent outlines a method for treating cancer in a subject by administering a therapeutically effective amount of the antibody.
Career Highlights
Jill Rillema is currently employed at Bristol-Myers Squibb Company, where she continues to advance her research and innovations. Her work is characterized by a commitment to developing novel therapeutic solutions that address critical health challenges.
Collaborations
Rillema collaborates with esteemed colleagues, including Maria Jure Kunkel and Subinay Ganguly, to further enhance her research efforts and drive innovation in the field.
Conclusion
Jill Rillema's contributions to biotechnology through her patents and research exemplify her dedication to advancing medical science. Her innovative work in gene identification and therapeutic development holds promise for future medical breakthroughs.