Jila Boal

Title: Jila Boal: Innovator in Nucleotide Chemistry

Introduction

Jila Boal is a notable inventor based in McLean, VA (US), recognized for his contributions to the field of nucleotide chemistry. He holds 2 patents that focus on innovative compounds used in oligonucleotide synthesis. His work has significant implications for various applications in molecular biology and biochemistry.

Latest Patents

Jila Boal's latest patents include groundbreaking compounds that enhance the functionality of hairpin oligonucleotides. One patent describes purines and pyrimidines linked to a quencher, which are compounds comprising purines substituted at the C-8 position and pyrimidines substituted at the C-4 position with a linker and quencher. These compounds, when incorporated into hairpin oligonucleotides, effectively quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide. Another patent focuses on pyrimidines linked to a quencher, detailing compounds that include pyrimidines substituted at the C-5 position with a linker and quencher. Similar to the first patent, these compounds can also be easily incorporated into oligonucleotides using conventional or automated oligonucleotide synthetic techniques.

Career Highlights

Throughout his career, Jila Boal has worked with reputable companies such as Intergen Company and Serologicals, Inc. His experience in these organizations has contributed to his expertise in nucleotide chemistry and oligonucleotide synthesis.

Collaborations

Jila Boal has collaborated with notable colleagues, including Glenn Nardone and Irena Nazarenko, who have contributed to his research and development efforts in the field.

Conclusion

Jila Boal's innovative work in nucleotide chemistry and his patents on nucleotide-quencher compounds highlight his significant contributions to the scientific community. His advancements in oligonucleotide synthesis continue to pave the way for future research and applications in molecular biology.