This inventor holds 4 USPTO granted patents and 2 published patent applications, plus 1 CIPO patent. Top assignee: Regeneron Pharmaceuticals, Inc.. Active years: 2022-2025.
Company Filing History:
Years Active: 2022-2025
Title: Jikang Wu: Innovator in Liquid Chromatography and Cell Culture
Introduction
Jikang Wu is a notable inventor based in Chappaqua, NY (US). He has made significant contributions to the fields of liquid chromatography and cell culture, holding a total of 4 patents. His work focuses on improving compound detection and characterization, as well as enhancing protein titer in cell cultures.
Latest Patents
Wu's latest patents include innovative methods for high confidence compound identification by liquid chromatography-mass spectrometry. These methods aim to improve compound detection and characterization by providing a sample to a liquid chromatography system capable of sample separation. The process generates sample components, which are then analyzed through multiplexed targeted selected ion monitoring (SIM) to create an inclusion list. Iterative mass spectral data-dependent acquisition (DDA) is performed from this list to identify individual sample components, thereby characterizing the sample effectively. In one application, multiplexed targeted SIMs and iterative MS2 DDA acquisition are utilized to enhance robust compound identification for cell culture medium analysis.
Another significant patent involves methods of improving recombinant protein titer and cell titer in cell culture. This innovation utilizes cell culture media with reduced impurities, specifically focusing on HEPES buffer and related impurities. The methods and media developed by Wu aim to improve protein titer, cell growth, and viable cell density, which are crucial for the production of recombinant proteins.
Career Highlights
Jikang Wu is currently employed at Regeneron Pharmaceuticals, Inc., where he continues to advance his research and innovations. His work has had a substantial impact on the pharmaceutical industry, particularly in the development of more effective methods for compound analysis and cell culture.
Collaborations
Wu collaborates with esteemed colleagues such as Hongxia Wang and Haibo Qiu, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Jikang Wu's contributions to liquid chromatography and cell culture represent significant advancements in the field. His innovative patents and ongoing work at Regeneron Pharmaceuticals, Inc. continue to influence the industry positively.