This inventor holds 2 USPTO granted patents and 5 published patent applications and 1 EPO patent. Top assignee: University of California. Active years: 2020-2021.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2020-2021
Title: Innovations by Jie Li in Protein Delivery Systems
Introduction
Jie Li is an accomplished inventor based in Los Angeles, CA. He has made significant contributions to the field of protein delivery systems, holding 2 patents that showcase his innovative approaches to enhancing therapeutic efficacy.
Latest Patents
One of Jie Li's latest patents is titled "Protein nanocapsules with detachable zwitterionic coating for protein delivery." This invention relates to protein nanocapsules that exhibit material properties that change in different in vivo environments. A zwitterion moiety on the surface of the nanocapsule can protect the protein from opsonization in a first environment, yet uncouples from the protein nanocapsule in a second environment, such as at a pH of less than 6.5. In embodiments of the invention, the uncoupled protein nanocarrier is then internalized by mammalian cells, including tumor cells.
Another notable patent is "Therapeutic hyperbranched polyglycerol encapsulated biomolecules." This patent discloses methods for modifying therapeutic agents, such as proteins, for improved oral, rectal, or transmucosal delivery. The therapeutic agents are conjugated to hyperbranched polymers, such as hyperbranched polyglycerol (HPG). When administered orally, the HBP protects the therapeutic agent from the acidic environment of the stomach and protease attack in the gastrointestinal tract, while facilitating absorption in the higher pH environment of the intestines. These methods and compositions are useful for the improved administration of various therapeutic agents.
Career Highlights
Jie Li is affiliated with the University of California, where he continues to advance research in the field of protein delivery systems. His work has garnered attention for its potential to improve therapeutic outcomes for patients.
Collaborations
Jie Li collaborates with notable colleagues, including Yunfeng Lu and Yang Liu, who contribute to his research endeavors and innovations.
Conclusion
Jie Li's innovative work in protein delivery systems exemplifies the potential of modern science to enhance therapeutic efficacy. His patents reflect a commitment to improving patient care through advanced biotechnological solutions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile