Jie Ku

Title: Innovations of Jie Ku in Pharmaceutical Chemistry

Introduction

Jie Ku is a notable inventor based in Suzhou, China, recognized for his contributions to pharmaceutical chemistry. He has been instrumental in developing processes that enhance the production of important pharmaceutical intermediates.

Latest Patents

Jie Ku holds three patents, showcasing his innovative approach in the field. His latest patents include a process for early sacubitril intermediates, which relates to a new enantioselective method for producing useful intermediates for NEP inhibitors or prodrugs. This invention specifically focuses on NEP inhibitors that comprise a γ-amino-δ-biphenyl-α-methylalkanoic acid or acid ester backbone. Another significant patent is for intermediates of neutral endopeptidase inhibitors and their preparation method. This invention also emphasizes a new process for producing intermediates for NEP inhibitors, particularly those with a g-amino-d-biphenyl-a-methylalkanoic acid or acid ester backbone.

Career Highlights

Jie Ku is currently employed at Novartis AG, where he continues to push the boundaries of pharmaceutical research. His work has significantly contributed to the development of new therapeutic agents.

Collaborations

Throughout his career, Jie Ku has collaborated with esteemed colleagues, including Yunzhong Li and David Hook. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.

Conclusion

Jie Ku's innovative work in pharmaceutical chemistry, particularly in the development of NEP inhibitors, highlights his significant contributions to the field. His patents reflect a commitment to advancing medical science and improving therapeutic options.