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Title: Innovations of Jianying Luo in Nucleic Acid Detection
Introduction
Jianying Luo is an accomplished inventor based in Boston, MA (US). He holds a total of 3 patents that focus on advancements in nucleic acid detection technologies. His work is particularly significant in the field of cancer research, where accurate detection of mutations can lead to better diagnostic and therapeutic strategies.
Latest Patents
One of Jianying Luo's latest patents is titled "High fidelity detection of nucleic acid differences by ligase detection reaction." This innovative method utilizes ligase detection reactions to distinguish minority templates in the presence of an excess of normal templates using a thermostable ligase. The process can be executed with a mutant ligase, thermostable ligase, or a modified oligonucleotide probe. This technique is especially beneficial for detecting cancer-associated mutations, as it provides a quantitative measure of the amount or ratio of the minority template. Another significant patent involves "Thermostable DNA ligase mutants," which employs similar methodologies to enhance the detection of nucleic acid differences.
Career Highlights
Throughout his career, Jianying Luo has made substantial contributions to the field of molecular biology and diagnostics. His innovative approaches have paved the way for more precise and reliable detection methods, which are crucial in the early diagnosis of various diseases, particularly cancer.
Collaborations
Jianying Luo has collaborated with notable professionals in his field, including Francis Barany and Marilyn Khanna. Their combined expertise has further advanced the research and development of nucleic acid detection technologies.
Conclusion
Jianying Luo's contributions to the field of nucleic acid detection are invaluable. His patents not only enhance the accuracy of cancer mutation detection but also represent significant advancements in molecular diagnostics. His work continues to influence the landscape of medical research and diagnostics.