Company Filing History:
Years Active: 2007
Title: Innovations of Jianwen Wei in Neurotoxin Research
Introduction
Jianwen Wei is a prominent inventor based in Guangzhou, China. He has made significant contributions to the field of neurotoxin research, particularly through his innovative work involving genes derived from sea snake venom. His research has implications for pain management and therapeutic applications.
Latest Patents
Jianwen Wei holds a patent for an invention that involves the identification and modification of three genes encoding short chain neurotoxins. These genes, named sn12, sn36, and sn160, were obtained through the construction of a cDNA library from the venom gland of sea snakes. The genes were amplified using the PCR method and subsequently cloned into the expression vector PETTRX. The neurotoxin genes were expressed in soluble fusion proteins in the BL21-DE3 strain, which was induced with IPTG. Studies demonstrated that the three recombinant short chain neurotoxins significantly increased the pain threshold in mice, showcasing their potential analgesic effects.
Career Highlights
Jianwen Wei is affiliated with Zhongshan University, where he conducts his research. His work has garnered attention for its innovative approach to understanding and utilizing neurotoxins for medical purposes. With a total of 1 patent, he continues to push the boundaries of scientific research in this area.
Collaborations
Jianwen Wei collaborates with notable colleagues, including Anlong Xu and Xiaofen Zhong. Their combined expertise enhances the research efforts and contributes to the advancement of knowledge in neurotoxin applications.
Conclusion
Jianwen Wei's innovative research in neurotoxin genes represents a significant advancement in pain management therapies. His contributions to the field highlight the importance of scientific exploration and collaboration in developing new medical solutions.