Jiansu Zhang

Title: Innovations and Contributions of Inventor Jiansu Zhang

Introduction

Jiansu Zhang, located in Roslindale, MA, is a noted inventor with a remarkable portfolio of four patents. His work primarily focuses on advancements in pharmaceutical methodologies that address critical health issues.

Latest Patents

Among Jiansu Zhang's latest patents is the invention titled "Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2." This invention highlights the discovery that prostaglandin D2 is the natural ligand for orphan receptor CRTH2, a finding pivotal for developing valuable pharmaceuticals. The patent details methods for screening therapeutic compounds aimed at treating PGD-related disorders, including allergy, asthma, and inflammation, alongside appropriate assay methodologies.

Another significant patent is the "Method for identifying validated target and assay combinations for drug development." This innovation involves methods that assist in identifying compounds or designing further compounds that produce a desired phenotype, such as growth inhibition. It employs constructed cells with a regulable gene encoding a biomolecule that modulates the function of a target component, allowing for extensive testing both in vitro and in vivo. Compounds identified through this process serve as potential candidates for drugs with desired activities.

Career Highlights

Jiansu Zhang has worked with various companies, including Cubist Pharmaceuticals, which has contributed to his extensive expertise in drug development and research. His experience in the pharmaceutical sector is invaluable, particularly in the innovation of methods that enhance the efficacy of drug discovery.

Collaborations

Throughout his career, Zhang has collaborated with notable professionals such as Francis P. Tally and Jianshi Tao. These partnerships have likely fostered an environment of shared knowledge and innovation, further enhancing his contributions to the field of pharmaceuticals.

Conclusion

With a focus on therapeutic compounds and drug development methodologies, Jiansu Zhang's patents represent significant strides in the biomedical field. His collaborations and career achievements emphasize his role as a leading inventor committed to advancing health science through innovation.