This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignee: The University of Texas System. Active years: 2003-2008.
Company Filing History:
Years Active: 2003-2008
Title: Innovations of Jianrong Lu in Cardiac Hypertrophy
Introduction
Jianrong Lu is a prominent inventor based in Quincy, MA (US), known for his significant contributions to the field of cardiac research. He holds 2 patents that focus on the regulation of cardiac gene expression, particularly in relation to cardiac hypertrophy. His work has the potential to impact the treatment and understanding of heart conditions.
Latest Patents
One of Jianrong Lu's latest patents involves methods and compositions relating to HDAC 4 and 5 regulation of cardiac gene expression. This invention defines the molecular events linking calcium stimulation to cardiac hypertrophy. It demonstrates that calcium stimulation of the hypertrophic response is mediated through an interaction between HDAC 4 and 5 with MEF2. Furthermore, it highlights that the phosphorylation of HDACs results in the loss of HDAC-mediated repression of MEF2 hypertrophic action. This patent provides methods and compositions for treating cardiac hypertrophy and identifying subjects at risk for this condition. Additionally, it includes methods for detecting compounds with therapeutic activity toward cardiac hypertrophy.
Career Highlights
Jianrong Lu is affiliated with the University of Texas System, where he continues to advance research in cardiac health. His innovative work has garnered attention in the scientific community, contributing to a deeper understanding of cardiac hypertrophy and its underlying mechanisms.
Collaborations
He has collaborated with notable researchers such as Eric N Olson and Timothy McKinsey, further enhancing the impact of his work in the field of cardiac research.
Conclusion
Jianrong Lu's contributions to cardiac hypertrophy research through his patents and collaborations highlight his role as an influential inventor in the medical field. His work promises to pave the way for new therapeutic approaches to heart conditions.