This inventor holds 2 USPTO granted patents. Top assignee: Academia Sinica. Active years: 2003-2006.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2003-2006
Title: Innovations of Jiann-Ruey Hong
Introduction
Jiann-Ruey Hong is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of aquatic biology through his innovative research and inventions. With a total of 2 patents, his work focuses on the regulation of apoptosis in aquatic organisms.
Latest Patents
One of Jiann-Ruey Hong's latest patents is titled "Regulation of apoptosis in aquatic organisms by aquabirnavirus." This invention provides a mechanism for studying apoptosis in aquatic organisms by infecting them with aquabirnavirus, particularly the infectious pancreatic necrosis virus (IPNV). The infection of IPNV in aquatic cells, such as Chinook salmon embryo cells (CHSE-214), converts these cells into apoptotic cells. The invention also includes a method for monitoring morphological changes during apoptosis by cloning EGFP, a variant type of GFP, into aquatic cells and observing fluorescence using microscopic techniques. The intensity of the fluorescence reflects the expression of EGFP in the cells. Furthermore, the invention offers means for inducing or preventing/rescuing apoptosis in hosts, including both aquatic and vertebrate species. Apoptosis can be induced by IPNV infection or VP3 transfection, with VP3 being a 32 kDa protein derived from IPNV segment A. The apoptosis can be prevented or rescued by an antisense VP3 RNA or a zfMcl-1a protein.
Career Highlights
Jiann-Ruey Hong is affiliated with Academia Sinica, where he conducts his research and develops his inventions. His work has garnered attention for its potential applications in understanding and managing aquatic health.
Collaborations
One of his notable collaborators is Jen-Leih Wu, who contributes to the research efforts in the field.
Conclusion
Jiann-Ruey Hong's innovative work in the regulation of apoptosis in aquatic organisms showcases the intersection of biology and technology. His contributions are vital for advancing our understanding of aquatic health and disease management.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile