Company Filing History:
Years Active: 2021-2025
Title: Jiangtao Ren: Innovator in Gene Editing Technologies
Introduction
Jiangtao Ren, an accomplished inventor based in Philadelphia, PA, is making significant strides in the field of gene editing. With a total of five patents to his name, Ren's work focuses on enhancing T cell functionality through innovative biotechnological methods. His research holds immense potential for advancing immunotherapies and improving treatment options for various diseases.
Latest Patents
Ren's most recent patents showcase groundbreaking methodologies in gene editing within T cells. The first patent, titled "Compositions and methods for gene editing in T cells using CRISPR/Cpf1," presents novel compositions and techniques aimed at modifying primary T cells. This invention encompasses the use of stem-loop Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) RNA alongside a Cpf1 enzyme, providing a new avenue for cellular modification.
Another noteworthy patent, "Modified immune cells having enhanced function and methods for screening for same," focuses on gene-edited immune cells, specifically T cells, which are equipped with exogenous T cell receptors (TCR) and/or chimeric antigen receptors (CAR). This invention creates immune cells with improved functions by introducing targeted modifications in endogenous gene loci that regulate T cell capabilities. The methods outlined in this patent also include techniques for screening TCR- or CAR-T cells, assessing their efficacy, memory, and persistence.
Career Highlights
Jiangtao Ren is currently affiliated with the University of Pennsylvania, where he endeavors to push the boundaries of genetic engineering and immunology. His work has led him to develop several innovative approaches that could reshape immunotherapeutic strategies, making him a notable figure in the field of gene editing.
Collaborations
In his research pursuits, Ren collaborates with esteemed colleagues such as Yangbing Zhao and Xiaojun Liu. Together, they form a dynamic team at the University of Pennsylvania, uniting their expertise to further enhance the potential of gene editing technologies and their applications in immunotherapy.
Conclusion
With five patents already attributed to his name, Jiangtao Ren exemplifies the spirit of innovation in the biotechnology field. His contributions to gene editing in T cells are not only advancing scientific knowledge but also paving the way for transformative treatments in medicine. As his research evolves, it holds the promise of offering new hope for patients in need of effective immunotherapies.
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