The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
May. 02, 2018
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Yangbing Zhao, Lumberton, NJ (US);
Jiangtao Ren, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12N 9/22 (2006.01); C12N 15/10 (2006.01); C12N 15/117 (2010.01); C12N 15/90 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); C12N 15/117 (2013.01); C12N 15/90 (2013.01); A61K 2039/5158 (2013.01); A61P 35/00 (2018.01); A61P 37/02 (2018.01); C12N 2310/122 (2013.01); C12N 2310/20 (2017.05); C12N 2310/315 (2013.01);
Abstract
The present invention includes compositions and methods for modifying primary T cells. In one aspect, the invention comprises administering to a cell a stem-loop Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) RNA (st-crRNA) and a Cpf1 enzyme.