Jian Qin

Title: Innovations by Inventor Jian Qin in Nucleic Acid Extraction and Analysis

Introduction

Jian Qin, an accomplished inventor based in Palo Alto, California, has made significant strides in the field of molecular biology. With a total of two patents to his name, his innovative work focuses on advancing technologies for nucleic acid extraction and analysis.

Latest Patents

Qin's latest patents showcase groundbreaking methods that enhance the extraction of nucleic acids from paraffin-embedded samples. One patent introduces a unique technology for isolating nucleic acids that surpasses the existing state of the art. Traditional protocols typically involve using organic solvents to dissolve wax-embedded samples. However, Qin's method employs hexadecane as the solvent, facilitating higher yields with less degradation. This approach results in a product that boasts an increased number of unique mRNA transcripts, making it ideal for subsequent sequencing and analysis.

His second patent outlines a novel method and apparatus for determining copy number variation using digital PCR. This technique estimates the concentration of DNA molecules in a biological sample by utilizing multiple reaction sites. The method stores the reaction sites in memory and distributes the sample among them, allowing for an accurate determination of DNA presence. Moreover, it computes a confidence interval for the estimated DNA concentration, adding a layer of precision to molecular analysis.

Career Highlights

Jian Qin is currently employed at Fluidigm Corporation, where he contributes to the company's mission to drive innovation in life sciences. His expertise has positioned him as a significant asset within the organization.

Collaborations

At Fluidigm Corporation, Qin collaborates with fellow researchers and innovators, including Ramesh Ramakrishnan and Peilin Chen. These collaborations enhance the research environment, fostering the exchange of ideas and advancing their collective work in improving molecular biology technologies.

Conclusion

Jian Qin’s contributions through his patents reflect a commitment to innovation and excellence in the field of molecular biology. His work not only advances scientific understanding but also provides practical solutions for more efficient nucleic acid extraction and analysis, positioning him as a notable inventor in today's research landscape.