Company Filing History:
Years Active: 2018-2025
Title: Innovations of Inventor Jian Gu
Introduction
Jian Gu is a prominent inventor based in Austin, TX, known for his significant contributions to molecular tagging and gene fusion detection technologies. With a total of 6 patents to his name, Gu has made strides in the field of biotechnology, particularly in methods that enhance the accuracy and efficiency of genetic analysis.
Latest Patents
One of Jian Gu's latest patents focuses on methods, systems, compositions, kits, apparatus, and computer-readable media for molecular tagging. This innovation involves a multiplex molecular tagging procedure that utilizes a variety of tags appended to polynucleotides. These tags possess unique characteristics, such as sequence and detectable moiety, allowing for the identification and tracking of individual tagged molecules within a mixture. This technology is particularly useful for generating error-corrected sequencing data and detecting low-abundance target polynucleotides in nucleic acid samples.
Another notable patent by Gu pertains to methods for partner agnostic gene fusion detection. This method amplifies a nucleic acid sample using a primer pool that targets multiple exon-exon junctions of a driver gene. The resulting amplicons are sequenced and aligned to a reference sequence, allowing for the detection of gene fusion events without prior knowledge of specific fusion partner genes or breakpoints.
Career Highlights
Jian Gu is currently employed at Life Technologies Corporation, where he continues to develop innovative solutions in the field of biotechnology. His work has significantly impacted the way genetic analysis is conducted, paving the way for advancements in medical research and diagnostics.
Collaborations
Throughout his career, Gu has collaborated with several talented individuals, including Kelli Bramlett and Dumitru Brinza. These collaborations have fostered a creative environment that encourages the exchange of ideas and the development of groundbreaking technologies.
Conclusion
Jian Gu's contributions to the field of biotechnology through his patents and innovative methods have established him as a key figure in genetic research. His work continues to influence advancements in molecular tagging and gene fusion detection, showcasing the importance of innovation in science and technology.