Jiaen Deng

Title: The Innovative Contributions of Jiaen Deng

Introduction

Jiaen Deng is a notable inventor based in Hong Kong, China. He has made significant contributions to the field of biological analysis, particularly in the study of circulating nucleic acids. His work has implications for understanding genetic properties and disease levels in biological samples.

Latest Patents

Jiaen Deng holds a patent titled "Determining linear and circular forms of circulating nucleic acids." This patent provides techniques for analyzing circular DNA in biological samples, such as cell-free DNA found in plasma. The process involves cleaving circular DNA to linearize it for sequencing. Techniques such as restriction enzymes and transposases are utilized for this purpose. The patent outlines criteria for identifying linearized DNA molecules, differentiating them from linear DNA. This innovation allows for the analysis of circular DNA molecules, including eccDNA and circular mitochondrial DNA, to measure various properties of biological samples.

Career Highlights

Throughout his career, Jiaen Deng has worked with prestigious institutions, including The Chinese University of Hong Kong and Grail, Inc. His experience in these organizations has contributed to his expertise in the field of nucleic acid analysis.

Collaborations

Jiaen has collaborated with notable colleagues, including Yuk-Ming Dennis Lo and Rossa Wai Kwun Chiu. These collaborations have furthered advancements in the understanding of circulating nucleic acids.

Conclusion

Jiaen Deng's innovative work in analyzing circulating nucleic acids has the potential to significantly impact the field of genetics and disease research. His contributions through patents and collaborations highlight his role as a leading inventor in this important area of study.