Company Filing History:
Years Active: 2022-2024
Title: Innovations of Ji Nie in DNA Analysis
Introduction
Ji Nie is an accomplished inventor based in Chicago, IL (US). He has made significant contributions to the field of DNA analysis, particularly through his innovative methods for amplifying bisulfite-treated DNA. With a total of 2 patents, his work is paving the way for advancements in genetic research.
Latest Patents
Ji Nie's latest patents focus on methods for the amplification of bisulfite-treated DNA. These methods, compositions, and kits provide a novel approach for whole genome, unbiased DNA analysis that can be performed on limited amounts of DNA. His techniques can be utilized to analyze DNA to determine its modification status. The process involves several steps, including ligating an adaptor to the DNA molecules, treating the ligated DNA with bisulfite, hybridizing the bisulfite-treated DNA with a primer, extending the hybridized primer to create double-stranded DNA, and finally, in vitro transcribing the double-stranded DNA to produce RNA.
Career Highlights
Ji Nie is affiliated with the University of Chicago, where he continues to advance his research in DNA analysis. His work has garnered attention for its potential applications in various fields, including genetics and molecular biology.
Collaborations
Some of Ji Nie's notable coworkers include Xiao-Long Cui and Chuan He. Their collaborative efforts contribute to the innovative research environment at the University of Chicago.
Conclusion
Ji Nie's contributions to the field of DNA analysis through his patented methods highlight his role as a leading inventor in this area. His work not only enhances our understanding of genetic material but also opens new avenues for research and application in biotechnology.